Dopaminergic and Serotonergic Genotypes and the Subjective Experiences of Hypnosis

Hypnotizability is related to the Val158Met polymorphism of the COMT gene. The authors’ aim was to find associations between candidate genes and subjective dimensions of hypnosis; 136 subjects participated in hypnosis and noninvasive DNA sampling. The phenomenological dimensions were tapped by the Archaic Involvement Measure (AIM), the Phenomenology of Consciousness Inventory (PCI), and the Dyadic Interactional Harmony Questionnaire (DIH). The main results were that the “Need of dependence” subscale of AIM was associated with the COMT genotypes. The GG subgroup showed higher scores, whereas AA had below average scores on the majority of the subjective measures. An association between the 5-HTTLPR polymorphism and the intimacy scores on the DIH was also evident. The effects are discussed in the social–psychobiological model of hypnosis.


The preparation of this article was supported by the Hungarian Scientific Research Funds (OTKA 109187 and K100845).

A Neutral Control Condition for Hypnosis Experiments: “Wiki” Text

A new control condition called Wiki is introduced. Key themes of each test suggestion of the Stanford Hypnotic Susceptibility Scale, Form C, were matched by a corresponding extract from The authors compared phenomenological reports of participants across 4 conditions: hypnosis split into high and low hypnotizable subgroups, music, and Wiki condition, using the Phenomenology of Consciousness Inventory. High hypnotizables undergoing hypnosis reported higher altered experience and altered states of awareness than individuals in the Wiki condition, supporting the authors’ hypothesis that the Wiki condition does not evoke an altered state of consciousness (internal dialogue, volitional control, and self-awareness did not differ). Wiki might be a viable control condition in hypnosis research given further examination.


This work was supported by the Hungarian Scientific Research Funds (OTKA 109187 and K100845).

Imagery Vividness Before and During the PCI–HAP: A Partial Replication

This study sought to replicate an earlier study wherein imagery vividness before and during a phenomenological hypnotic assessment procedure was assessed, while also measuring trance (hypnoidal) state effects and several other variables. Correlational and regression analyses for that study suggested that imagery vividness during hypnotism was predicted by combined imagery vividness before hypnotism and trance (altered) state effects during hypnotism. The present study procured a larger sample employing a similar design and a similar subject pool. With the current study, although trance state effects and imagery vividness before hypnotism still significantly predicted hypnotic imagoic suggestibility (imagery during hypnotism), the variance accounted for was appreciably less. The meaning of these results as a function of the methodology used is discussed.